Objective To study the benefit of combination angiotensin converting enzyme inhibitor ( ACEI) and angiotensin type 1 receptor antagonist ( ATl1) therapy in diabetic nephropathy. 目的评价血管紧张素Ⅰ转换酶抑制剂(ACEI)和血管紧张素Ⅱ受体1拮抗剂(ATla)联合治疗糖尿病肾病(DN)伴高血压的临床价值。
Evidence show that statins, angiotensin-converting enzyme inhibitors, angiotensin II type 1 receptor antagonist, calcium channel blockers have a strong intracellular antioxidant activity. 有证据表明,他汀类药物、血管紧张素转换酶抑制剂类药物、血管紧张素Ⅱ受体1抑制剂及钙通道阻滞剂均有强大的细胞内抗氧化活性。
Combinative application of angiotensin-converting enzyme inhibitors and angiotensin II antagonist 血管紧张肽转换酶抑制剂与血管紧张肽II受体拮抗剂的联合应用
METHODS: The changes in sum of money of consumption, DDDs and daily cost of angiotensin converting enzyme inhibitor ( ACEI) and angiotensin ⅱ receptor antagonist during the period 2000~ 2002 were collected and analyzed. 方法:对2000年~2002年3年中消耗的血管紧张素转换酶抑制剂(普利类)和血管紧张素Ⅱ受体拮抗剂(沙坦类)的用药金额、用药频度及日均费用的变化进行统计分析。
Objective: To investigate the renal protection and protective effect of Losartan and Enalapril, an angiotensin converting enzyme inhibitor and an angiotensin receptor antagonist, at very small doses against proteinuria in primary glomerulonephritis. 目的:探讨小剂量血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂对原发性肾小球肾炎的抗尿蛋白作用和对肾脏的保护作用。
Objective To observe the relationship between TGF β_1 and diabetic osteoporosis in experimental rats, and to explore the effects of angiotensin converting enzyme inhibitor ( ACEI)-fosinopril and angiotensin ⅱ receptor antagonist ( ATRA)-losartan on osteoporosis. 目的了解转化生长因子(TGF)β1与糖尿病性骨质疏松症之间的关系,及血管紧张素转换酶抑制剂福辛普利和血管紧张素Ⅱ受体拮抗剂氯沙坦对骨质疏松症的治疗作用。
In recent years, clinical studies have shown that angiotensin-converting enzyme inhibitors and β-blockers can improve symptoms and reduce mortality; angiotensin ⅱ antagonist and aldosterone antagonist spironolactone also play a role. 近年来临床研究证明血管紧张素转换酶抑制剂和β受体阻滞剂能改善患者的症状并降低死亡率;血管紧张素Ⅱ拮抗剂和醛固酮拮抗药螺内酯也起一定的作用。